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Inflammatory bowel disease (IBD)

Inflammatory bowel disease - IBD

Inflammatory bowel disease (IBD)

Inflammatory bowel disease > Ulcerative colitis >> Crohn's disease

Constipation can also be a sign of inflammatory bowel disease, which comes in either of two forms: ulcerative colitis and Crohn's disease. The constipation that is present in these cases is due to bowel obstruction and slowed transit.

Inflammatory bowel disease is mediated by the immune defenses in an individual's body. Our body has a remarkable trait of being tolerant towards the normal bacteria residing in the digestive tract, but in the presence of other ingested pathogens, the body immediately mounts up immune defenses to eliminate the invaders swiftly. However, in this idiopathic inflammatory bowel disease, this tolerance towards the normal intestinal microflora becomes disrupted, resulting to defects in the mucosa. Thus, the pathogenesis of both conditions is both an interaction of both external (otherwise called exogenous, such as luminal flora) and host factors. Although these diseases share the same mechanism of pathogenesis, they have very different clinical manifestations. Its incidence varies among different locations, but it is more common in developed countries. The peak age for their onset is between the ages of 15 and 30 years old, with a second peak age reported to be between 60 and 80 years old.

To initially differentiate ulcerative colitis (UC) and Crohn's disease (CD), let us first describe them briefly. Ulcerative colitis is a chronic disease which is due to inflammation limited to the colon and the rectum, while Crohn's disease is an autoimmune condition affecting any portion of the gastrointestinal tract, but most often affecting the distal part of the small intestine as well as the colon. To be able to understand these conditions clearly, let us take these up one by one.
Constipation in children Constipation in children

The treatment for both ulcerative colitis and Crohn's diseas are very extensive, and requires a great deal of money depending on its severity. One cannot even assess accurately his or her risk for colon cancer once these have started, since its being chronic in origin poses more threats – and more possibilities - for complications. Genetics also play a role in the presence of these diseases, since there are reports that it runs in families, and it has associations with some genetic syndromes. But then, regardless of these genetic tendencies, the quality of life is very useful in the evaluation of patients with inflammatory bowel disease. Preventive measures are still particularly important in order to avoid these alarming diseases, all of which merit special medical attention. Since smoking is largely an exogenous factor, this should be avoided! In conjunction with intake of the right amounts of fluid and fibers, inflammatory bowel diseases become relatively out of reach.

Inflammatory bowel disease > Ulcerative colitis >> Crohn's disease

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